• Association of smoking and cancer with the risk of venous thromboembolism: the Scandinavian Thrombosis and Cancer cohort 

      Paulsen, Benedikte; Gran, Olga Vikhammer; Severinsen, Marianne T.; Hammerstrøm, Jens; Kristensen, Søren Risom; Cannegieter, Suzanne C.; Skille, Hanne; Tjønneland, Anne; Rosendaal, Frits; Overvad, Kim; Næss, Inger Anne; Hansen, John-Bjarne; Brækkan, Sigrid K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-21)
      Smoking is a well-established risk factor for cancer, and cancer patients have a high risk of venous thromboembolism (VTE). Conflicting results have been reported on the association between smoking and risk of VTE, and the effect of smoking on VTE-risk in subjects with cancer is scarcely studied. We aimed to investigate the association between smoking and VTE in subjects with and without cancer in ...
    • Effect of lower-leg trauma and knee arthroscopy on procoagulant phospholipid-dependent activity 

      Touw, Carolina E.; Nemeth, Banne; Lijfering, Willem M.; van Adrichem, Raymond A.; Wilsgård, line; Latysheva, Nadezhda; Ramberg, Cathrine; Nelissen, Rob G. H. H.; Hansen, John Bjarne; Cannegieter, Suzanne C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-08)
      Background: Lower-leg injury and knee arthroscopy are both associated with venous thromboembolism (VTE). The mechanism of VTE in both situations is unknown, including the role of procoagulant microparticles. This may provide useful information for individualizing thromboprophylactic treatment in both patient groups.<p> <p>Objective: We aimed to study the effect of (1) lower-leg trauma and (2) ...
    • Existing data sources in clinical epidemiology: The Scandinavian Thrombosis and Cancer Cohort 

      Jensvoll, Hilde; Severinsen, Marianne T.; Hammerstrøm, Jens; Brækkan, Sigrid Kufaas; Kristensen, Søren R.; Cannegieter, Suzanne C.; Blix, Kristine; Tjønneland, Anne; Rosendaal, Frits Richard; Dziewiecka, Olga; Overvad, Kim; Næss, Inger Anne; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-16)
      Background: Although venous thromboembolism (VTE) is a known common complication in cancer patients, there is limited knowledge on patient-related and cancer-specific risk factors in the general population. The Scandinavian Thrombosis and Cancer (STAC) Cohort was established by merging individual data from three large Scandinavian cohorts (The Tromsø Study, the second Nord-Trøndelag Health Study, ...
    • Impact of incident venous thromboembolism on risk of arterial thrombotic diseases 

      Lind, Caroline; Flinterman, Linda E.; Enga, Kristin; Severinsen, Marianne T; Kristensen, Søren R; Brækkan, Sigrid Kufaas; Mathiesen, Ellisiv B.; Njølstad, Inger; Cannegieter, Suzanne C.; Overvad, Kim; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-11-22)
      BACKGROUND: Growing evidence supports an association between venous thromboembolism (VTE) and arterial thrombotic diseases (ie, myocardial infarction and ischemic stroke). We aimed to study the association between VTE and future arterial events and to determine the population attributable risk of arterial events by VTE in a large prospective cohort recruited from the general population. METHODS AND ...
    • The increased risk of venous thromboembolism by advancing age cannot be attributed to the higher incidence of cancer in the elderly: the Tromsø study 

      Blix, Kristine; Brækkan, Sigrid Kufaas; Le Cessie, S.; Skjeldestad, Finn Egil; Cannegieter, Suzanne C.; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Long-Term Incidence of Venous Thromboembolism in Cancer: The Scandinavian Thrombosis and Cancer Cohort 

      Gade, Inger Lise; Brækkan, Sigrid Kufaas; Næss, Inger Anne; Hansen, John-Bjarne; Cannegieter, Suzanne C.; Rosendaal, Frits Richard; Overvad, Kim; Hindberg, Kristian; Hammerstrøm, Jens; Gran, Olga Vikhammer; Tjønneland, Anne; Severinsen, Marianne T.; Kristensen, Søren R (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-06)
      The risk of venous thromboembolism (VTE) in patients who survive the first years after a cancer diagnosis after the acute effects of disease and treatment in comparison to a similar background population has been sparsely investigated. The aim of the study was to investigate if incidence rates (IRs) of VTE differed in patients who were alive at least 2 years after a cancer diagnosis without VTE ...
    • Prediction of recurrent venous thrombosis in all patients with a first venous thrombotic event: The Leiden Thrombosis Recurrence Risk Prediction model (L-TRRiP) 

      Timp, Jasmijn F.; Brækkan, Sigrid Kufaas; Lijfering, Willem M.; van Hylckama Vlieg, Astrid; Hansen, John-Bjarne; Rosendaal, Frits Richard; le Cessie, Saskia; Cannegieter, Suzanne C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-11)
      <i>Background</i> - Recurrent venous thromboembolism (VTE) is common. Current guidelines suggest that patients with unprovoked VTE should continue anticoagulants unless they have a high bleeding risk, whereas all others can stop. Prediction models may refine this dichotomous distinction, but existing models apply only to patients with unprovoked first thrombosis. We aimed to develop a prediction ...
    • Rosuvastatin treatment decreases plasma procoagulant phospholipid activity after a VTE: A randomized controlled trial 

      Ramberg, Cathrine; Hindberg, Kristian; Biedermann, Joseph S.; Cannegieter, Suzanne C.; van der Meer, Felix J.; Snir, Omri; Leebeek, Frank W. G.; Kruip, Marieke J. H. A.; Hansen, John Bjarne; Lijfering, Willem M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-25)
      Background - Venous thromboembolism (VTE) is a frequent cardiovascular disease with severe complications, including recurrence and death. There is a great need for alternative prophylactic treatment options as anticoagulation is accompanied by increased bleeding risk. Statins are reported to reduce the risk of incident and recurrent VTE, but the mechanisms are elusive. Procoagulant phospholipids ...
    • Survival after cancer-related venous thrombosis: the Scandinavian Thrombosis and Cancer Study 

      Crobach, Monique J.T.; Anijs, Rayna J.S.; Brækkan, Sigrid Kufaas; Severinsen, Marianne T.; Hammerstrøm, Jens; Skille, Hanne; Kristensen, Søren R.; Paulsen, Benedikte; Tjønneland, Anne; Versteeg, Henri H.; Overvad, Kim; Hansen, John Bjarne; Næss, Inger Anne; Cannegieter, Suzanne C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-28)
      Patients with cancer have an increased risk of developing venous thromboembolism (VTE), and this combination is reported to result in poorer survival compared with cancer alone. This study aimed to investigate the impact of VTE on the survival of patients with cancer in a general population. The Scandinavian Thrombosis and Cancer (STAC) cohort, a population-based cohort including 144 952 participants ...